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KMID : 1098420060140060317
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Korean Journal of Medicinal Crop Science
2006 Volume.14 No. 6 p.317 ~ p.321
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Increase Effect of Anticancer Activities on Rhodiola sachalinensis A. Bor by the Change of Extraction Process
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Kim Cheol-Hee
Kim Hyo-Sung
Kwon Min-Cheol
Bae Geun-Jung
Ahn Ju-Hee
Lee Hak-Ju
Kang Ha-Young
Lee Hyeon-Yong
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Abstract
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This study was performed to compare effect of anticancer activities on Rhodiola sachalinensis by ultrasonifi-cation process and solvent. Compared the yield to the water extracts (WE), wafer extracts with ultrasonification (WEU) at60, loot and ethyl alcohol extracts (EE), ethyl alcohol extracts with ultrasonification (EEU) at 60 {circ}C from Rhodiola sachalinensis. Experimental studies were progressed through the anticancer activities such as cell cytotoxicity, inhibition activities of cell growth. The cell cytotoxicity using human embryonic kidney cell (HEK293) was showed cytotoxicity of below 26.26%by extracts of Rhodiola sachalinensis in 1.0 mg/ml concentration, The anticancer activities were increased in over 70% by extracts of Rhodiola sachalinensis in A549, AGS, Hep3B and MCF-7 cells. From the results, the extract Rhodiola sachalinensis were showed useful anticancer activities.
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KEYWORD
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anticancer activities, Rhodiola sachalinensis, ultrasonification
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